The combined value of farms, ranches, and rural real estate for sale in Hughes County, South Dakota, recently on Land.com was almost $11 million. This represents almost 1,000 acres of farms, ranches, hunting land and other land for sale in Hughes County. Hughes County ranks 20th out of 66 counties in South Dakota for the total number of acres of land currently advertised for sale. Of all locations in Hughes County with land and rural real estate for sale, Pierre featured the most land for sale. Government and state-level services are the main economic drivers in Hughes County. Hughes County is South Dakota's 42nd biggest county (800 square miles). It's located in the Great Lakes South Dakota region of South Dakota.