Land for sale in Shelby County, Missouri, recently totaled $5 million and almost 1,000 acres. Shelby County ranks 113th out of 115 counties in the state for the total acreage of land currently advertised for sale. Shelbina featured the most land for sale. Agriculture and farming drives the Shelby County economy, with 709 farms recorded in the county during the U.S. Census in 2012. Farming activities in Shelby County generate annual revenues of $18 million, most of which is from crops. Shelby County is the 86th largest county (502 square miles) in Missouri. It's located in the Northeast Missouri region of the state.